Poyle is a largely industrial and agricultural area in the unitary authority of Slough, in the ceremonial county of Berkshire, England (of which it is the easternmost settlement). It is located 18 miles (29 km) west of Charing Cross in London and immediately west of the M25 motorway, near Heathrow Airport; it also adjoins the Colne Valley regional park.
Historically in Middlesex, Poyle was transferred to Surrey in 1965 and to Berkshire in 1995. Together with the neighbouring village of Colnbrook to the west, it forms the Colnbrook with Poyle civil parish.